In the UK, the leading cause of death in men, since 2001, has been heart disease. For women, the leading cause of death is dementia, primarily caused by Alzheimer’s. The risk of both heart disease and Alzheimer’s can be greatly lessened through physical exercise.
Why am I telling you this?
Simple: go ride your bicycle! Your very life probably depends on it!
Extend your life, while having fun - go cycle touring!

So you want to cycle a UK-based coast to coast route, but get away from the crowds, find solitude, and want to be totally self-reliant, along a route that's far from boring, and presents more challenging surfaces to ride on?
This is the route you want:

I started doing a serious of route guides for UK coast to coast routes (of which there are quite a number).
Of course, this simply MUST start with the most popular one: the C2C.
If you've cycled it, please add a comment, telling us about your ride?

I actually have a few books for which I've still to write a review. In the meantime, if you're looking for good cycling related reading material, here's a great place to start:

If you ever thought of going cycle touring, you'll have many questions.
This posts (or the ones it links to) will answer a great many of your questions:

Proper Planning Prevents Piss Poor Performance - the very well-known 6P principle, but do YOU apply it when planning adventures?
Do you plan for what to do when things go wrong?

Woohoo! Postie delivered my Sawyer water filtration device. That's going to come in SO handy on camping trips, and when cycle touring!